Though knowledge of thalassaemia and sickle cell disease has improved steadily for half a century, these inherited haemoglobulinopathies still present a highly significant public health challenge, particularly in the developing world. Though some important advances in specific therapies such as stem cell transplantation have increased the potential for a cure, improvements in daily management remain central to improving the quality of life of patients.

This is a postgraduate text, which will be invaluable to trainees and residents in haematology, haematologists in practice and healthcare professionals treating those with sickle cell disease and thalassaemia. The contributors cover basic science and epidemiological aspects of the public health challenge, but maintain a focus on the day to day issues encountered in dealing with affected people. A comprehensive picture of care management is presented, including diagnostic, therapeutic, and psychosocial aspects. Also included is a separate section of self-assessment questions designed to help candidates prepare for examinations in haematology. Containing clear, practical advice, this text is an essential, practical resource to bridge the gap between expensive reference texts and smaller manuals.